KLF5 appears to fuel pancreatic cancer metastasis by reprogramming epigenetic controls, offering a potential new therapeutic target.

Colorectal liver metastases (CRLM), cancer that has spread from the colon or rectum to the liver, have a deadly reputation. Due to its pervasive spread, typical cancer treatments like chemotherapy and ...

Scientists have discovered why ovarian cancer spreads so rapidly through the abdomen. Cancer cells enlist normally protective abdominal cells, forming mixed groups that work together to invade new ...

Many patients with metastatic cancers receive therapy that is initially highly effective, often resulting in complete remission. However, cancer cells have a remarkable capacity to evolve resistance ...

Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing ...

Veronica Paulus is a former STAT intern supported by the Harvard University Institute of Politics. After patients go into remission, there may still be undetected cancer cells lying dormant through ...

The results of a preclinical study by researchers at Baylor College of Medicine have uncovered a strategy that triple negative breast cancer (TNBC) cells use to boost their ability to metastasize.

Group of human colon cancer cells with invasive behaviour. Cell nuclei are in yellow and cell bodies in red. The finger-like protrusions of invasive cells are on the upper right region. "The origin of ...

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical ...

An Indian review reveals how macrophages are reprogrammed inside breast tumours, helping cancer grow and spread while opening new treatment pathways.