Researchers have identified a specific protein complex inside neurons that tags toxic tau fragments for destruction, offering the clearest explanation yet for why certain brain cells survive while ...

Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).

Scientists from Mass General Brigham and the Broad Institute of MIT and Harvard have used CRISPR screens to identify genetic modifications that influence T cell function and survival in cultures and ...

In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Künzel, Associate Director in the Functional Genomics department at AstraZeneca, about the application of arrayed ...

An artistic rendering of CRISPR-enhanced T-cells attacking a tumor. Research has shown that the gene-editing system CRISPR can modulate T cell behavior to make them better cancer killers without ...

Fred Hutch researchers invent a CRISPR screening method to understand RNA-binding proteins often mutated in cancer and other diseases In biology’s standard tale of two acids — deoxyribonucleic (DNA) ...

The brain is often referred to as a "black box" - one that's difficult to peer inside and determine what's happening at any given moment. This is part of the reason why it's difficult to understand ...

Using a new CRISPR-based methodology for modulating DNA structure to enact epigenetic control over specific genes, a team of researchers has identified a “master regulator” gene capable of improving T ...

Muscles make up nearly 40% of the human body and power every move we make, from a child's first steps to recovery after injury. For some, however, muscle development goes awry, leading to weakness, ...

This figure shows the structure of PTGES3. The research team made the association after creating a fluorescent tag that tracks androgen receptor levels in real time. The androgen receptor is a hormone ...