Pasca Lab specializes in growing three-dimensional organoid models from reprogrammed stem cells, which capture molecular changes during fetal brain-like development. Because the human brain cannot be ...

Researchers have developed a model that rapidly converts stem cells to brain cells with protein structures characteristic of Parkinson's disease (PD), enabling the study of the condition's unique and ...

Neuroscientists discover that Rett syndrome mutations cause a leaky brain via overexpressed miRNA-126-3p, pointing to a new therapeutic target for vascular repair.

Every year, around 15 million babies worldwide are born before 37 weeks of gestation. Being born preterm can disrupt development, and earlier births increase the risk of life-changing health outcomes.

A stem-cell-based "organ-on-a-chip" model of ALS mimics early biological changes seen in the degenerative disease.

Like the seeds of a forest, a few cells in embryos eventually sprout into an ecosystem of brain cells. Neurons get the most recognition for their computing power. But a host of other cells provides ...

Some parts of our bodies bounce back from injury in fairly short order. The outer protective layer of the eye—called the cornea—can heal from minor scratches within a single day. The brain is not one ...

The human brain can do many amazing things, but self-repair is not one of its repertoire of abilities. Once neurons die—from trauma, stroke, or disease—they rarely grow back. Scientists have been ...

Neurons from grafted stem cells contain intrinsic codes for navigating and forming connections, which may improve cell therapy for a brain short-circuited by stroke. Some parts of our bodies bounce ...

Illustration showing a transplanted nerve cell (gold) using its internal compass (code) to find its partner nerve cells in the brain and spinal cord (green). Some parts of our bodies bounce back from ...