The reversible conjugation of ubiquitin chains to protein substrates regulates almost every cellular process. Ubiquitin chains can be assembled via one of the seven ubiquitin Lys residues (which are ...
Figure 1: Schematic overview of polyubiquitin chains and linkage-specific assembly. Subsequent studies demonstrated that UBE2C could also function in the context of human APC to promote Lys11-linked ...
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