A single treatment of viral vector-delivered CAR-A construct in mice with existing plaque saturation cut the amount of amyloid plaques in half.

Researchers engineered astrocytes with chimeric antigen receptors to remove amyloid beta plaques linked to Alzheimer’s. In mouse studies, a single injection prevented plaque formation when given early ...

Researchers engineer CAR-astrocytes to target and remove amyloid plaques in Alzheimer’s, showing a 50% reduction in brain ...

Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...

A new study reveals that astrocytes—star-shaped support cells traditionally viewed as passive partners of neurons—play a ...

Astrocytes in the cerebellum trigger a shift in GABA signaling during late adolescence, enabling adult-level motor coordination.

Astrocytes shed their supportive role and unlock hidden neurogenic potential, offering new hope for brain injury recovery through cutting-edge epigenetic reprogramming. Study: DNA methylation controls ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Scientists at Washington University in St. Louis have engineered brain cells to hunt and destroy amyloid plaques, cutting toxic buildup by roughly half in aged mice with advanced Alzheimer’s-like ...