LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Animal models from the Jackson Laboratory are available that reflect the genetic diversity of human populations. Taking genetic diversity into account is particularly important in basic research or ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Monash University scientists have challenged the conventional wisdom that biological patterns are explained by physical constraints. In a study published today in Science, the researchers present ...

In a recent study published in the Frontiers in Neuroendocrinology journal, researchers assessed the impact of hormonal contraceptives (HC) on the brain and stress. Hormonal contraceptives have ...

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

New computer models predict the risk of side effects from heart drugs more accurately than animal models. Researchers from the University of Oxford (UK) have developed computer simulations that are ...

Preclinical testing is vital for assessing the safety profiles and potential efficacy of new therapeutics in development. Animal testing is one of two routes usually selected for the preclinical stage ...

I recently read a highly-detailed, comprehensive, science-based report called The Research Modernization Deal 2021. It unambiguously shows that numerous experiments on nonhuman animals (animals) fail ...